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Studies in cultured hepatocytes and in vivo

Excessive amounts of ROS may be a primary cause of biomolecular oxidation

We then present a discussion of ferritin as one out of several acute-phase biomarkers (Section 4) together with the biological and the possible clinical role of the acute-phase reaction and acute-phase mediators for the initial pretreatment prognostication (Section 5), the regulation of inflammation/coagulation in AML (Section 6) and the prognostication for AML patients receiving allogeneic stem cell transplantation (Section 7)