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Notably, tumor angiogenesis plays a crucial role in the occurrence of drug resistance in breast cancer

Copper chelators can reverse copper-induced immunosuppression and enhance infiltration of CD8 + T and NK cells ( As a newly identified form of cell death, the direct link between disulfidptosis and the immune microenvironment remains unclear

These effects are highest during the titration phase, typically peaking around weeks 6-8 of use, and resolve for the majority of participants as the body adapts, usually by week 10-12

3-PLG-ibu-A-GSH) nanocarriers (yellow) and Golgi apparatus (magenta) in brain endothelial cells