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conversely, myxoedematous (hypothyroid) cretinism, the less prevalent form, exhibits attenuated cognitive impairment, growth retardation, thyroid hypofunction, alongside diverse somatic manifestations including dry and coarse skin texture, hoarse vocalization, and delayed pubertal development [122,123,124,125]

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Several factors can increase your risk of experiencing muscle spasms or cramps, including: Age: Older adults are more prone to muscle spasms due to loss of muscle mass and reduced muscle function, which may begin in the mid-40s and accelerate with inactivity

International journal of molecular sciences .Aug 2 2022;23(15)doi:10.3390/ijms23158574