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(99) analyzed the antiproliferative properties of polyphenols present in water and ethanol extracts of grape leaves on various cancer cell lines such as MCF-7 breast cancer cells, and HepG2 human hepatoma cells

Abbreviations EGCG Epigallocatechin 3-gallate AD Alzheimer's disease PD Parkinson's disease (A) Amyloid peptide COX-2 Cyclooxygenase 2 MMP-9 Matrix metalloproteinase-9 NF-B Nuclear Factor Kappa B ERK1/2 Extracellular signal-regulated kinases1/2 H 2 S Hydrogen sulfide CH 3 SH Methyl mercaptan ROS Reactive oxygen species H 2 O 2 Hydrogen peroxide VEGF Vascular endothelial growth factor NHL Non-Hodgkin lymphomas TNF Tumor necrosis factor EGFR Epidermal growth factor receptor Authors contributions All authors have read and agreed to publish the current version of the manuscript

10.1016/j.redox.2016.01.010 283 ValdiviaA.Prez-lvarezS.Aroca-AguilarJ

Cell lines and culture conditions LLC/1 (Lewis Lung Carcinoma) and B16-F10 (Melanoma) cell lines were cultured following the American Type Culture Collection ( recommendations and standard methods