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Generally, more work is needed to evaluate whether fast proliferating cells in the body, such as in the bone marrow have also a higher sensitivity to ferroptosis

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TB-500 binds monomeric G-actin via the LKKTETQ motif, modulating the actin pool available for cytoskeletal remodeling and cell migration

Hydroxyl radicals are formed by incubating Fe +3 - EDTA premixture with ascorbic acid and H 2 O 2 at pH 7.4, causing 2-deoxy-d-ribose degradation and generating a malondialdehyde (MDA)-like product