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For example, studies have identified inflammatory markers such as GlycA as being strongly associated with both the onset and persistence of depression, offering a promising direction for biomarker research in this domain [201]

DHX15, a DEAH-box RNA helicase, plays a pivotal role in spliceosome remodeling and RNA metabolism (27, 28)

Using advanced tracer methodologies, the researchers identified a fascinating metabolic phenomenon they termed "brain glucose steal." Due to systemic mitochondrial impairment, non-brain organs were essentially stealing glucose intended for the central nervous system, starving the brain of energy and driving cognitive dysfunction

The amphiphilic nature of COXP enables the molecule to undergo self-assembly to form a micelle with a CMC value of 3.9 M