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Directly, many substances in cigarette smoke possess cytotoxic properties that induce oxidative stress, a critical pathway in liver injury and fibrosis [5]

"Before now, we had a large body of epidemiological evidence linking smoking with cancer, but now we can actually observe and quantify the molecular changes in the DNA due to cigarette smoking," first author Ludmil Alexandrov said in a press release

in fact it is more likely to reinforce the second one, as nobody likes to feel they ought to, or are being expected to do something

More than 500,000 Americans live with lung cancer and 234,030 new cases are diagnosed annually, causing 25 percent of cancer deaths