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for the rest of the countries (for which no data in CIA Factbook 33 exist nor logical neighbour countries to which to relate the trend) the data was extrapolated over time by scaling the last available value to reflect subsequent regional GDP 32 changes

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IFN- binds to the IFN-/ receptor on the producing cell itself or on neighboring cells, which causes the amplification of iNOS expression and NO production through the signal transducer and activator of transcription (STAT)-mediated signaling [123] (Figure 9)

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