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Carnitine translocase and transferase components Carnitine/AcylCarnitine translocase Mitochondria import acylcarnitines through carnitine/acylcarnitine translocase (CACT) located in the inner mitochondrial membrane, which catalyzes a mole-to-mole exchange of carnitines/acetylcarnitines and acylcarnitines 56

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Thus, many treatments that are believed to improve mitochondrial function have been shown to be helpful for some children with ASD

BBB dysfunction is considered a key mechanism through which peripheral inflammation contributes to CNS pathology in ASD, allowing inflammatory molecules and immune cells to infiltrate neural tissue and exacerbate neuroinflammation (Sochocka et al., 2019)