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The code used in this part is similar to that in GitHub ( Data collection and analysis were not performed blind to the conditions of the experiments

BMC Cancer (2021) 21(1):1343

FIGURE 9 Discussion Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease characterized by a complex pathogenesis involving multiple interrelated processes, including intestinal barrier disruption, oxidative stress imbalance, excessive inflammatory activation, gut microbiota dysbiosis, and metabolic disturbances ( Body weight loss, colon shortening, and histological damage are hallmark pathological features of the DSS-induced UC model and serve as key metrics for evaluating therapeutic interventions

As a result, the immobilized cells on loofah sponge could be reused five times over a period of 526 h, and lag phase was only detected in the first batch and the fermentation period was significantly shortened, increasing the yield and productivity of -PL from 22.53 g/L and 3.30 g/L/day to 34.11 g/L and 9.34 g/L/day, respectively [106]