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This therapy is non-pharmacologic, opioid-free and devoid of systemic side effects

unilateral ureteral obstruction (UUO) mice, GPX4 declined faster post-IRI and failed to recover by day 28, reflecting model-specific ferroptosis kinetics

Xenograft implantation of HCT116 cells All the protocols for animal experiments in this study were approved by the Experimental Animal Committee of Keio University School of Medicine (the approved number

A separate ligament study (Cerovecki et al., 2010, Journal of Orthopaedic Research ) reported improved medial collateral ligament healing in rats over 90 days post-transection, with effective dosing observed across intraperitoneal, oral, and topical routes