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A key contributor to this process is the pro-inflammatory cytokine IL-1, which is significantly elevated in aging individuals [568]

Additional preclinical safety evaluation and regulatory toxicology research may help clarify how findings observed in experimental models translate to human biology

We used a 7 Tesla (T) BioSpec 70/30 horizontal magnetic resonance imaging (MRI) scanner (Bruker BioSpin, Ettlingen, Germany)

Because phenolic ligands were traditionally employed in insulin formulations due to their bacteriostatic properties , their additional role as protein-stabilizing agents and their elegant structural role in the hexamer represents the value of serendipity as a source of therapeutic advance