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Disclosures: Mazen Almasry: Nothing to Disclose, Elizabeth Townsend: Nothing to Disclose, Hiep Phan: Nothing to Disclose, Adnan Said: Mallinckrodt: Speaking and Teaching 1835 MACHINE LEARNING RADIOMICS BASED ON CT TO PREDICT RESPONSE TO LENVATINIB PLUS PD-1 INHIBITOR FOR HEPATOCELLULAR CARCINOMA Zhiyuan Bo 1 Zhengxiao Zhao 2 Xiaozai Xie 3 Yi Wang 3 Zhiyuan Bo 3 , 1 the First Affiliated Hospital of Wenzhou Medical University, 2 Zhejiang Chinese Medical Hospital, 3 Wenzhou Medical University Background: Lenvatinib plus PD-1 inbibitor has been widely used for unresectable hepatocellular carcinoma (uHCC), meanwhile a complex heterogeneity leads to a limited response rate