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L2-Cmu development and validation To target IGF-1R action in mice, we utilized the mAb, L2-Cmu (Amgen Inc, Thousand Oaks, CA), which is a murinized IgG1 version of the fully human L2-C mAb previously reported by Calzone et al

If the cause of B12 deficiency is unclear, testing for intrinsic factor antibodies (and sometimes parietal cell antibodies) can help diagnose pernicious anaemia, an autoimmune condition affecting B12 absorption

This protein, often overexpressed on the membranes of certain cancer cells, plays a critical role in the progression of malignancies