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Description

Thompson et al., 1993

[] Heavy metals, mainly lead, may also substitute bivalent cations such as calcium ion (Ca2+), magnesium ion (Mg2+), iron (II) (Fe 2 +) and monovalent cations such as sodium ion (Na+) and cause dysfunctions where these cations act as cofactors in various enzyme activities

Vascular Recruitment and Gastrointestinal Tract Healing." Curr Pharm Des

This ratio indicates that VVZ-2471 readily crosses the blood-brain barrier and achieves significant concentrations in the brain, classifying it as a drug with high brain tissue distribution 45