MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 5-FAM azide is an excellent

5-FAM azide is an excellent alkyne-reactive fluorescent reagent for labeling azide-containing biological molecules through click chemitry

Product Name DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C100H150N14O25 Molecular Weight 1948

Product Name Pomalidomide-CO-C4-alkyne Synonyms Pomalidomide-4'-CO-C4-alkyne CAS Number n/a Related CAS Molecular Formula C20H19N3O5 Molecular Weight 381

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody–drug conjugate (ADC) development

MC-Val-Cit-PAB(m-PEG8)-Exatecan m-peg4 5-FAM azide is an excellentSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,