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Comparative studies with the terminal alkene probe showed reduced labeling of protein targets

Glutamine metabolism thus promotes cytokine production, including interferon- (IFN-) and IL-2, through the activation of mTORC1 and c-Myc, contributing to potent anti-tumor responses (72)

Therefore, local glutamate/glutamine dysregulation could be used as a biomarker of HIV infection, be exploited in potential treatments, and could also explain the increased susceptibility of infected individuals to several types of cancer that may also use glutamine/glutamate as a major source of energy to survive 22,94

SELENOP maintains the activity of glutathione peroxidase 4 (Gpx4) by binding to LRP-1, preventing lipid peroxidation and ferroptosis, both of which contribute to neurodegeneration in AD [15]