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Cardiovascular protection represents another area of investigation

To improve the bioavailability of these compounds, several advanced formulation strategies have been explored [163]

10.1152/japplphysiol.00233.2016 51 CirulliF.BerryA.ChiarottiF.AllevaE

They are regulated by the PI3K-AKT-mTORC1 pathway, which mediates their translocation to the Golgi apparatus, where they are cleaved to release active transcription factors