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In cancer, lactate, an energy source and metabolic by-product, can shuttle between glycolytic tumor cells and oxidative tumor cells, thereby promoting tumor occurrence and development ( In vivo , lactylation at H4K12la promotes expression of Hif1 and enhances endometrial glycolysis, and in turn forms an H4K12la-Hif1-glycolysis feedback loop to drive decidualization ( Notably, pyruvate dehydrogenase kinase 4 (PDK4) mRNA expression exhibits significant upregulation during in vitro decidualization

Glutamine and glucose metabolism during thymocyte proliferation

It increases the number of beneficial bacteria, such as Parvibacter, Enterorhabdus, and Akkermansia , attenuating the inflammatory response in DSS-induced mouse models (Cheng et al., 2023)

Methods of use: Wet your skin with lukewarm water