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doi: 10.1159/000328516

Conventional pharmacologic migraine treatments often meet with limited success and may have intolerable side effects or be contraindicated with other common co-existing conditions (Chaibi 2011a

Based on the efficacy and safety records in T2DM, attention has been given to the repurposing of metformin as part of adjunct therapy for the treatment of cancer, age-related diseases, inflammatory diseases and COVID-19

Currently, several methods that effectively inhibit the occurrence of parthanatos by clearing lipid peroxides have been confirmed, such as using -tocopherol (-TOC) and ALOX12/15 inhibitors [144]