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Arab journal of urology

267,268 Under oxidative stress conditions, Nrf2 dissociates from Keap1 following thiol modifications of its cysteine residues, preventing Nrf2 ubiquitination and proteasomal degradation

Among these biomarkers, 8-OHdG and 8-OHG emerge as prominent oxidative byproducts formed when hydroxyl radicals and superoxide anions interact with the guanine bases eighth carbon atom in DNA and RNA