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Thus, maternal NR supplementation appears to orchestrate a coordinated microbiota restructuring that both activates microbial NAD biosynthesis and augments SCFA production, collectively sustaining host NAD utilization and metabolic adaptation to meet the high energetic demands of reproduction and lactation

Given the minimal anticipated risks, the study duration is limited, and the endpoints do not involve severe morbidity or mortality

Reported Side Effects Epithalon is generally well-tolerated, with most users reporting minimal to no side effects

More data is needed to better understand the safety and efficacy of KPV in humans