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The rats were euthanized under ketamine/xylazine (3:1) anesthesia, and liver tissues were immediately removed and washed with cold phosphate-buffered saline and kept at 80 C for subsequent studies

coli bacteria show sensitivity to ceragenin in the range of 18 g/mL (Wnorowska et al., 2022)

Extrapolation from animal models to human physiology is not scientifically validated, and no safety conclusions can be drawn from preclinical findings alone