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Trends Microbiol (2023)

Tesamorelin hepatotoxicity profile

Chronic dehydration makes blood thick and viscous, which is extremely difficult for the heart to pump through narrow pelvic arteries

In a TAC rat model, TSA (10 mg/kg) improved cardiac function, alleviated cardiac hypertrophy and decreased collagen deposition, effects dependent on miR-618 induction (inhibition of miR-618 abolished the protective effects of TSA) (132)