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Hormone levels in women drop most dramatically during perimenopause (immediately before menopause) and during menopause

So during transplant there's a lot of changes in the immune system

Other Therapies Clinical studies have also demonstrated a modest benefit for other pharmacological treatments including venlafaxine (Effexor), tramadol (ConZip), amitriptyline (Elavil), opioids, oxcarbazepine (Trileptal), and topical amitriptyline, baclofen, lidocaine, or ketamine, as well as non-pharmacological treatments including massage, non-invasive neuromodulation, acupuncture/acupressure, and aromatherapy (Dan 2024)