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This loss of chronobiological responsiveness stems both from the desynchronization between central and peripheral clocks, and from the chronotype heterogeneity observed with aging, as the geriatric tendency toward morning chronotypes may not align with dosing regimens designed for younger adults with evening chronotypes (Kara et al., 2023)

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Also, do not begin taking any supplements without first consulting your healthcare provider, especially if you have adrenal fatigue or any major health condition