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New Zealands government has emphasised the role HTP could play in enabling New Zealand to reach its Smokefree 2025 target.[31] Compared with cigarette smoke, HTP are likely to expose users and bystanders to lower levels of particulate matter and harmful and potentially harmful compounds In a landmark move in 2020, the Food and Drug Administration authorised that IQOS, an HTP produced by Philip Morris, could be marketed as a modified risk product, indicating that the product was less harmful than smoking.[32] A 2024 cross-sectional survey of 502 users of HTP assessed the impact of this product on the American market, finding that HTP use helped them to reduce or quit their cigarette intake.[33] Can the success of HTP be repeated across lower- and middle-income countries

Because the risk of liver failure is more common with propylthiouracil, methimazole is most often the first choice

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