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Concluding remarks The levels and compartmentalization of NAD + dictate energy state that impinges on normal physiological and biological responses, as indicated by the regulatory role of NAD + in proper redox homeostasis, genomic stability, gene expression, circadian clock, inflammation, metabolism, cellular bioenergetics, mitochondrial homeostasis and adaptive stress responses

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Individual results will vary based on factors including age, baseline health condition, consistency of use, genetic factors, and other individual variables

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Circulation 137 , 22742277 (2018)

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