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As a co-factor in carboxylase enzymes, Biotin is involved in gluconeogenesis, fatty acid synthesis, and the metabolism of amino acids

[6] Hu S, Rayman MP

[DOI] [PMC free article] [PubMed] [Google Scholar] 271.Moskaug JO, Carlsen H, Myhrstad M, Blomhoff R

(2) dissociation of tumor cells from the primary tumor mass, (3) invasion of the neighboring tissue, (4) intravasation into pre-existing and newly formed blood and lymph vessels, (5) transport through the vessels, (6) extravasation from the vessels, (7) establishment of circulating tumor cells (CTCs) and the disseminated cells at a secondary anatomical site, where they can stay dormant for a prolonged period of time, (8) metastatic outgrowth of micrometastases and macrometastases creating clinically detectable secondary tumors and neoplastic process [13]