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[PubMed] [Google Scholar] 173.Peterson CD, et al

Many of the adverse events attributed to peptides trace back to contaminated or mislabeled research-grade products, not the peptides themselves

Contributing mechanisms include direct tubular toxicity of snake venom metalloproteinases and phospholipase A2, intravascular haemolysis with haemoglobinuria, rhabdomyolysis with myoglobinuria, disseminated intravascular coagulation (DIC) with intrarenal microthrombosis, and pre-renal injury secondary to hypotension and third-space fluid losses

These findings revealed the higher expression level of regeneration gene 3 (reg3) in gastric cancer cells with HP-CagA +