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Biomed Pharmacother 107:14801487 Iyer MK, Niknafs YS, Malik R et al (2015) The landscape of long noncoding RNAs in the human transcriptome

Cisplatin (cis-[Pt(NH 3 ) 2 Cl 2 ]), while commonly used as a cancer treatment, can have toxic effects on the kidneys and liver

Unlike CRISPR, which uses only one guide RNA (gRNA), the Cas-CLOVER endonuclease system employs two gRNAs along with the Clo051 nuclease activity, which relies on the dimerization of subunits linked to each gRNA