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These findings suggested that DMB may act through inhibiting NF-B signaling pathway to inhibit the inflammation in intestine and alleviate UC development

283,284,285 PEG modification can inhibit the binding of apolipoprotein E to LNPs, a key mechanism for LNP uptake by the liver, thereby affecting liver uptake of LNPs

Others have connected dysfunctional ELS with the dissemination and seeding of pTau, further implicating this system in tauopathies (Tanaka et al., 2019