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Hence, in general, the stability of formyl- and/or oxidized forms is much higher than that of methyl- and/or reduced ones, and the acidic environment accelerates the thermal decomposition 66,106,234,346,363,364,365,366,367,368,369,370,371,372,373,374

Using a combination of protein crystallography and native MS, we have determined both the binding site and pose of two novel ligands, directly quantifying their effect on SOD1 dimerization and predicting their mode of action

The normal duration of this self-limited infection is 710 days, and it can be fatal [58]

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