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ROS generation contributes to the activation of MLKL during necroptosis in lung cancer cells [131] and serves as a downstream event triggered by MLKL upon the induction of necroptosis in colon adenocarcinoma cells [132]

Cancer Cell 38:167197 Li Q et al (2016) The effects of buthionine sulfoximine on the proliferation and apoptosis of biliary tract cancer cells induced by cisplatin and gemcitabine

As we experience an age-related depletion of this precious compound, our cells become more vulnerable