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Initially characterized in a groundbreaking study published in Cell (Baar et al., 2017), FOXO4-DRI demonstrated promising senolytic activity in mice

In GSE100499, there were 942 upregulated and 437 downregulated genes, and there were 334 upregulated and 690 downregulated genes in GSE4105

Often referred to as the "master antioxidant," glutathione is a molecule found in nearly every cell of the human body

So rather than make you go through all of those reviews to find them, here is a brief summary of the main areas where FOXO4-DRI serves useful via its senescence-destroying properties Increased Energy Another surprising finding in the 2017 Cell paper was increased activity within the mice who were genetically engineered to experience accelerated aging: A second unexpected observation was found in the behavior of the treated mice