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Other benefits, such as improved sleep quality, enhanced mood, or cognitive improvements, may develop more gradually over several days or weeks of treatment

You want to know whether those changes are the peptide doing its job, or just better lighting and a filter

By the mid-2000s, the obesity pharmacotherapy field expected at least 5% placebo-subtracted weight loss for regulatory consideration, a threshold later codified in FDA's 2007 guidance for industry on developing obesity drugs