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We found that the C11 halogen modulated affinity across all three opioid receptors: the 11-F compound 22 exhibited greater affinity compared to the parent 7OH, but this gain in binding was progressively lost as the halogen became larger (compounds 23 and 24 , Table 1)

The blue-emission CDs bearing abundant hydroxyl and carboxyl functional groups were quenched in the presence of Hg 2+

Overall, there were no differences in ECAR in any condition or in response to injection of glucose (G), oligomycin (O), or 2 deoxy-D-glucose (2DG) (see the cartoon in Fig