Drug Delivery to the Brain: Physiological Concepts, Methodologies and Approaches (AAPS Advances in the Pharmaceutical Sciences Series, 33) [Hardcover] de Lange, Elizabeth C.M.; Hammarlund-Udenaes, Margareta and Thorne, Robert G. label_15 books The Horse and His Boy

Drug Delivery to the Brain: Physiological Concepts, Methodologies and Approaches (AAPS Advances in the Pharmaceutical Sciences Series, 33) [Hardcover] de Lange, Elizabeth C.M.; Hammarlund-Udenaes, Margareta and Thorne, Robert G. label_15 books The Horse and His BoyThe development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the bloodbrain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e. g. active passive transport across the BBB, intra brain distribution, and central systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions

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