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Effect of high-dose ascorbic acid on vasopressors requirement in septic shock

Harris IS, Treloar AE, Inoue S, Sasaki M, Gorrini C, Lee KC

With the development of omics technologies, metabolomics plays an increasingly important role in the pharmaceutical industry and clinical applications, especially in drug development and treatment

These findings suggest that research into the therapeutic modulation of FOXO4 activity, such as through the use of the synthetic peptide FOXO4-DRI, could provide insight into the heart's natural protective mechanisms and degenerative changes associated with aging