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CoQ10 may help prevent heart failure, high blood pressure, high cholesterol, and diabetes

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Preclinical studies have evaluated KD primarily in SOD1 transgenic mouse models, which exhibit progressive motor neuron degeneration, muscle weakness, and mitochondrial dysfunction, thereby recapitulating key features of disease progression [40, 102]

The negative results of the latter study may, at least partly, be due to the large heterogeneity of causes of AKI (trauma, hypertension, surgery, drugs or sepsis) and/or the delayed initiation of rhIGF-1 treatment, i.e., after established AKI