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Birth Defects Research 114:551558 Keen JH, Habig W, Jakoby W (1976) Mechanism for the several activities of the glutathione S-transferases

Furthermore, to robustly quantify the transcriptomic similarity between tumor cells and myeloid cells, we calculated at single cell resolution multiple metrics, including Manhattan and Euclidean distance metrics, the Cosine and Pearson correlation-based directional similarity metrics, as well as the Phi and Bray-Curtis proportionality and compositional dissimilarity metrics 22,23

We also describe various applications and advantages of this Cys-targeted proteomics method and alternative approaches to overcome potential limitations of this method in studying oxidized proteins from MDMA-exposed tissues