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The mechanism of lysozyme depends on two acidic residues, Asp52 and Glu35

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Food and Drug Administration (FDA) in 1994, metformin has become a first-line treatment for type 2 diabetes mellitus (T2DM) ( 2 Materials and methods The literature review was conducted using various databases including Scopus, Web of Science, PubMed, Directory of Open Access Journals (DOAJ), ClinicalTrials.gov, and Science Direct

These physical barriers likely contribute to treatment resistance and warrant continued investigation of penetration-enhancing strategies tailored to CRC-specific microenvironmental features