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For instance, BTSA1, a known activator of BAX, has showcased promising antitumor activity in acute myeloid leukemia (AML) cells and is currently under investigation for its potential synergistic effects when combined with other drugs, aiming to enhance its efficacy and combat resistance (Reyna et al., 2017)

Its classification as a Group 1 carcinogen by the International Agency for Research on Cancer underscores its profound implications for human health (25)

Multiple factors are involved in this altered visceral sensation including dysbiosis, braingut communication, diet, psychological factors, genetic predisposition, inflammation and immunological factors

- and -tocopherols are the most abundant isoforms in both the diet and tissues (Fig