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Vitiligo Research: What New Treatments Are on the Horizon? Which Vitamin Deficiency Causes White Spots on the Skin? Glossitis and hyperpigmentation of hands due to Vitamin B12 deficiency. B12 leads to melanin synthesis more frequently in people with darker skin. Skin hyperpigmentation was reversed with B12 replacement Which Vitamin Can Stop Vitiligo Kayakalp Global
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