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Busy Seasons: When your sleep is less than ideal and your stress is higher than usual, your internal antioxidant reserves can be depleted more quickly

glucose oxidation preference Laboratory protocols use metabolic caging systems, Seahorse respirometry, and enzyme activity assays

Reduced Stress and Anxiety Modulates cortisol release May reduce sympathetic nervous system overactivation Anecdotal reports of calmness without fatigue 3

Expression of Cyp7a1, the rate-limiting enzyme of BA synthesis, was significantly increased by re-feeding similarly in WT/ND mice and Insr P1195L/ +/ND mice, while that in WT/HFD mice was significantly elevated under fasted condition and did not show further increase by re-feeding