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In this context, several sensors and pathways regulating the transcription factors, such as activator protein 1 (AP-1), cAMP response element-binding protein (CREB), hypoxia inducible factor-1 (HIF-1), nuclear factor B (NF-B), activating transcription factor 4 (ATF-4), and nuclear factor-erythroid 2-related factor-2 (Nrf2), have been described (Marinho et al

Data was complete with respect to baseline donor and recipient demographics and clinical follow-up to 1 year for the trial cohort (including patient and graft survival, graft function, and adverse event data)

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FT is a hollow globular protein shell composed of two types of subunits: ferritin heavy chain 1 (FTH1) and ferritin light chain (FTL) ( 3+ in the form of Fe 2 O 3 nH 2 O ( RAS -harboring cancer cells are more sensitive to ferroptosis, partly because RAS can down-regulate the expression of FTH1 and FTL, increasing intracellular LIP (Yang and Stockwell, 2008)