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Compared with traditional meta-analysis using linear mixed effect models, MR-BRT relaxes the assumption of a log(linear) relationship between exposure and risk, incorporates between-study heterogeneity into the uncertainty of risk estimates, handles estimates reported across different exposure categories, automatically identifies and trims outliers, and systematically tests and adjusts for bias due to study designs and characteristics

For example, one longer-term observational study yielded a somewhat complicated outcome: Individuals with moderate to severe anxiety experienced improvement, but those with milder anxiety became slightly more anxious

[43] 15 U.S.C

The valve attachment is screw-on, which is fine for everyday inflating, but a (literal) pain for cold fingers to manipulate in extreme weather