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To further evaluate the colonic tissue microenvironment in this setting, we then performed 960-plex RNA-ISH (CosMx from Nanostring) on our FFPE TMA at subcellular resolution, as recently described 39,40 (Fig

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In addition to enhancing serotonin levels, NAC attenuated neuroinflammatory markers (e.g., IFN-), increased GST activity, and reduced DNA damage, highlighting its broad neuroprotective effects in toxicological contexts

Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y (2004) Neuron-specific Apolipoprotein E4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice