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Patients received an initial median dose of approximately 0.1 mg/kg body weight of fondaparinux sodium injection, which translates into a median dose of 1.37 mg in the less than 20 kg weight group, 2.5 mg in the 20 kg to less than 40 kg weight group, 5 mg in the 40 kg to less than 60 kg, and 7.5 mg in the greater than or equal to 60 kg weight group

The company, however, does not publicly show the dissolution testing needed to validate that full-tract release claim

Ethics declarations Ethics approval and consent to participate The study protocol was approved by the ethics committee of Guilan University of Medical Sciences (IR.GUMS.REC.1400.197) in accordance with the World Medical Associations code of ethics (Declaration of Helsinki, revised in Brazil 2013), and registered at an ICMJE and WHO recognized registry of clinical trials (www.irct.ir) at 28/08/2021 (registration number: IRCT20200920048782N1)

The Core Difference: Preservative vs No Preservative Bacteriostatic water contains 0.9% benzyl alcohol, a preservative that inhibits bacterial growth and allows multi-dose use over 28 days