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It has crucial impacts on the growth and diseases of the abovementioned organisms ( 2.1 Iron accumulation Iron is crucial for various life activities of cells ( Figure 1 ) ( Figure 1 Excessive free iron leads to iron accumulation, which triggers nonenzymatic, iron-dependent Fenton chain reactions that directly produce excessive reactive oxygen species, thereby causing oxidative damage to cells ( Figure 1 )

It carries the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH and ends in a C-terminal amide that defines the kisspeptin RFamide family